27 April 2026
Fezolinetant is a first-in-class non-hormonal medicine that targets the brain’s thermoregulation pathway to reduce moderate to severe hot flushes, making it a helpful option for those who can’t, or prefer not to, use hormones. Early real-world use suggests it can start working within weeks, and it can be combined with lifestyle strategies like sleep, stress support, and cooling techniques for a more comfortable day-to-day.
